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Date:         Mon, 7 Jan 2002 06:40:23 -0700
Reply-To:     "Stanley A. Gorodenski" <vvgsgor@DE.STATE.AZ.US>
Sender:       "SAS(r) Discussion" <SAS-L@LISTSERV.UGA.EDU>
From:         "Stanley A. Gorodenski" <vvgsgor@DE.STATE.AZ.US>
Subject:      Re: Statistical Significance of Change in Virus Levels
Content-Type: text/plain; charset=us-ascii

This looks like it could be a factorial analysis design of patients by drug dose by time. If so, that would be a better alternative. Stan

Melanie Barish wrote:

> Hello all - I am assuming some statistical duties temporarily, and I am > pretty rusty at it. I have a sample of data from of study of virus levels > in blood over time. There are 5 groups of patients, each having a > different drug dose, and measurements were taken over 8 time points. I > need to find out if the changes in virus levels are significant. I want > to do this for each patient overall, looking at overall change from 1st > measurement to last. I also want to look at change at each time point. > And at some point, I need to compare the significance between dosing > regimens. > > My question is this: Is the t-test the best method for me to do this? I > know it tests the significance between means for two populations. I > technically have only one population though. If the t-test is not the > right test, can you suggest one that I can use? > > Thanks in advance, > > Melanie > > ***************************************** > Melanie J Barish > Clinical Programmer Analyst > Progenics Pharmaceuticals, Inc > > 914-789-2864 > mbarish@progenics.com > *****************************************


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