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Date:         Wed, 29 Nov 2006 21:42:38 -1000
Reply-To:     Conchologists List <CONCH-L@LISTSERV.UGA.EDU>
Sender:       Conchologists List <CONCH-L@LISTSERV.UGA.EDU>
From:         David Lum <davidkwlum@HAWAII.RR.COM>
Subject:      Re: conus toxin
In-Reply-To:  <004701c71354$09a18770$6501a8c0@don7>
Content-Type: text/plain; charset="us-ascii"

All,

Perhaps the reason why a conotoxin is more potent in the teeth than when it is in the venom sac has to do with a reaction with a component in seawater. While a conotoxin remains in the venom sac of a particular species, it has no effect on the animal carrying it; however, if that animal has the same conotoxin injected into its tissues it can die. I've seen Conus textile envenomize and kill each other in an aquarium. A similar phenomenon may occur with cowfish and boxfish. These fish have glands that can secrete toxins. Under normal conditions, the fish do not suffer from their own toxicity. However, when one of these fishes is stressed, the poisons it releases are very potent and can even kill the fish that secreted them if it does not quickly move away from its chemical cloud. I've observed this from collecting Ostracion meleagris and Lactoria fornasini.

Regards, Dave

-----Original Message----- From: Conchologists List [mailto:CONCH-L@LISTSERV.UGA.EDU] On Behalf Of Don Barclay Sent: Tuesday, November 28, 2006 3:17 PM To: CONCH-L@LISTSERV.UGA.EDU Subject: Re: conus toxin

The toxin will still be active in a freshly-dead or frozen cone snail. Boiling breaks down the venom components. So, theoretically, you could envenomate yourself, if you were dissecting the animal or otherwise managed to get stuck with one of the teeth, or probably if you could get the venom into a cut. If you've read up on conotoxins you may already know that the venom in the teeth is several times as potent as that in the duct or bulb, at least in several species, and maybe all species. The researchers are still trying to figure out why this is so, unless they already did and I didn't hear about it....

Cheers,

Don

----- Original Message ----- From: David Herman To: CONCH-L@LISTSERV.UGA.EDU Sent: Tuesday, November 28, 2006 5:54 PM Subject: conus toxin

I've asked this question about conus in the past and never got a straight answer. Is it possible to be harmed by the conus toxin while cleaning dead conus, if you have a cut or any other method. David

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