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Date:         Wed, 21 May 2008 11:25:09 -0700
Reply-To:     Al <ali6058@GMAIL.COM>
Sender:       "SAS(r) Discussion" <SAS-L@LISTSERV.UGA.EDU>
From:         Al <ali6058@GMAIL.COM>
Organization: http://groups.google.com
Subject:      Phase 1 (Oncology)
Comments: To: sas-l@uga.edu
Content-Type: text/plain; charset=ISO-8859-1

Hi I am woking on Phase1(oncology) and i have few questions 1.Is it the SAS Programmer who decide Maximum Tolerable Dose(MTD) and Dose Limiting Toxicity by using the SAS reports?

2.For example if a Patient gets say dose 5.0 (day1 day2 and day3) on visit1 and dose 6.0 (day1 , day2 and day3) on visit2 and again dose 5.0(day1 day2 and day3 ) on visit3 which category of doses(5 or 6) this patient fall under if i were to code a demog table by dose

If any one of you has worked on phase 1 dose escalation protcols.Please provide me some insights

Thanks in advance


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