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Date:         Tue, 14 May 1996 17:11:07 +1300
Reply-To:     Will Hopkins <will.hopkins@STONEBOW.OTAGO.AC.NZ>
Sender:       "SAS(r) Discussion" <SAS-L@UGA.CC.UGA.EDU>
From:         Will Hopkins <will.hopkins@STONEBOW.OTAGO.AC.NZ>
Subject:      Help! Proc mixed simple example

I am struggling with the syntax of the contrast statement in proc mixed. I have a simple data set consisting of a between-subject factor with two levels (group: control and expt) and a within-subject factor with four levels (time: 1, 2, 3 and 4). The data were generated to give a difference between the control and expt groups at times 3 and 4 (i.e. corresponding to an intervention with the exptal group between times 2 and 3). This is a very standard, straightforward design.

Several weeks ago someone at SAS suggested I look at the worked example in the Technical Report P-229. Well, I have. It is for a split plot design, and quite simply it blows me right out of the water. A pity there isn't a simpler example.

Anyway I have tried the following. It works for the overall effect of group*time (it gives almost the same p value as the standard glm repeated-measures analysis), but the p value for the contrast of the interaction at time 3 vs time 2 is way too high. What am I doing wrong?

I should add that I have tried two consultant statisticians here. They also have difficulties coming to terms with proc mixed and have been unable to help.

proc mixed; class id group time; model var=group time group*time; repeated/subject=id type=cs; contrast 'interaction time 2 vs time 1' group*time 1 -1 0 0 -1 1 0 0; contrast 'interaction time 3 vs time 2' group*time 0 1 -1 0 0 -1 1 0; contrast 'interaction time 4 vs time 3' group*time 0 0 1 -1 0 0 -1 1; lsmeans group time group*time;

Will

Will G Hopkins PhD <will.hopkins@stonebow.otago.ac.nz> Physiology and Physical Education University of Otago, Dunedin, NEW ZEALAND Be creative - break rules.


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