Is there any way to do paired t-tests without setting up a separate variable for each comparison? I have months 1-4 in column 1 and drugs 1+2 in col 2 with my endpoints in other columns. I want to compare drug 1 in months 1+2 with a paired t-test, without having to make separate varaibles ( month1drug1, month2 drug1...) Any help would be greatly appreciated Thank you Jeff Mather