Date:         Tue, 5 May 1998 16:01:33 -0400
Reply-To:     Victor Kamensky <kamensky@AECOM.YU.EDU>
Sender:       "SAS(r) Discussion" <SAS-L@UGA.CC.UGA.EDU>
From:         Victor Kamensky <kamensky@AECOM.YU.EDU>
Subject:      DIMACS Workshop on Combinatorial Clustering and Multi-Domain
              Protein Structure Analysis (fwd)
Content-Type: text/plain; charset="us-ascii"

>Date: Tue, 5 May 1998 14:14:36 -0400 (EDT)
>From: Tonguc Unluyurt <tonguc@av.rutgers.edu>
>To: combcluster-list@av.rutgers.edu
>Subject: DIMACS Workshop on Combinatorial Clustering and Multi-Domain
Protein Structure Analysis (fwd)
>
>
>
>
>
>--------------------------------------------------------------------------
>| DIMACS: Center for Discrete Mathematics & Theoretical Computer Science |
>| A National Science Foundation Science and Technology Center            |
>
>--------------------------------------------------------------------------
>DIMACS Workshop on Combinatorial Clustering and Multi-Domain Protein
>                     Structure Analysis
>
>                     June 26-27, 1998
>DIMACS Center, CoRE Building (Room 431), Rutgers University, Busch Campus,
>                     Piscataway, NJ
>
>Principal Organizers:
>
>   * Sylvia Spengler, Lawrence Berkeley Nat. Lab, Life Sciences Div.
>   * Manfred D. Zorn, Lawrence Berkeley Nat. Lab, National Energy Research
>     Scientific Computing Division
>   * Inna Dubchak, Lawrence Berkeley Nat. Lab, National Energy Research
>     Scientific Computing Division
>   * Fred Roberts, Rutgers University, DIMACS
>   * Ilya Muchnik, Rutgers University, DIMACS
>   * Casimir A. Kulikowski, Rutgers University, CS Department
>
>Presented under the auspices of the Special Year on Massive Data Sets and
>the Special Year in Mathematical Support for Molecular Biology.
>----------------------------------------------------------------------------
>
>The combinatorics, graph theory and algorithms branches of discrete
>mathematics are powerful techniques for use in analysis of diverse sets of
>data. Combinatorics introduces clustering models, forms a basis for the
>interpretation of results, and brings new ideas to clustering methods. The
>area of combinatorial clustering provides new opportunities for systematic
>(routine) and comprehensive study of very large databases containing highly
>complex non-regular elements. However, researchers developing methods for
>combinatorial clustering often do not collaborate with specialists in the
>creation, management and analysis of large, complex databases.
>
>The goal of this workshop is to foster and facilitate such a collaboration
>by focusing on a particular application. The specific problem we wish to
>address is in the area of protein structure and analysis of multi-domain
>proteins (as an example for other type of interactions among large
>bio-molecules). By hosting this workshop, our aim is not only to stimulate
>research at the interface between these disciplines, but also stimulate
>development of ideas and methods in each field.
>
>We plan to have two type of sessions: theoretical, devoted to mathematical
>models and clustering procedures, and practical, concentrated on
>sequence-structure relations in biomolecular systems, mostly on multi-domain
>protein analysis.
>
>Following applications of clustering to the multi-domain protein analysis
>will be discussed among others:
>
>   * amino acid sequence segmentation which determines domain structures of
>     proteins,
>   * automatic procedure to collect libraries of protein domains,
>   * contact map method for protein 3D-structure analysis and protein fold
>     classification,
>   * inter-domain contact aggregates,
>   * correlation between contact structures and sequence segmentation.
>
>Confirmed speakers include:
>
>   * Israel Gelfand and Alexander Kister, Math., Rutgers Univ., NJ
>   * Alex Shneider, Invention-Machine, Co., MA
>   * Manfred Zorn, Lawrence Berkeley Nat.Lab, CA
>
>Contributed talks:
>If you would like to attend and give a talk or present a poster, please
>email an one page abstract in ascii format to Ilya Muchnik at
>muchnik@dimacs.rutgers.edu by May 14, 1998. There will be a small amount of
>support available for participants who do not have other sources of support
>available. Acceptance notification will be given by May 31, 1998.
>
>Workshop Registration:
>Due to limited space you must be registered to attend the workshop.
>You can register on line at
>http://www.dimacs.rutgers.edu/Workshops/CombCluster
>or by filling out the registration form and sending it to
>pravato@dimacs.rutgers.edu.
>----------------------------------------------------------------------------
>           DIMACS Center; Rutgers University;  96 Frelinghuysen Rd.;
>                         Piscataway, NJ 08854-8018
> TEL: 732-445-5928 FAX: 732-445-5932  **  EMAIL:center@dimacs.rutgers.edu
>                       WWW:  http://dimacs.rutgers.edu
>
>   DIMACS is a partnership of Rutgers University, Princeton University,
>AT&T Labs - Research, Bellcore, Bell Laboratories and NEC Research Institute
>
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