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Thank you very much for your valuable suggestions mam.

On Fri 23 Aug, 2019, 9:19 PM Lachele Foley, <[log in to unmask]> wrote:

> I haven't built force field params in a while, so others might have
> better (more recent) information than what I'm about to say.  You will
> need to use GAFF for the parameters except for the partial charges.
> You will need to translate the parameters for the atom types in the
> rest of the monosaccharide.  It will probably be best to generate a
> frcmod file containing the gaff params you need that bridge the type
> naming systems.  After that, you will need to make a best-guess
> initial charge set and, based on that, compute a better,
> ensemble-averaged set of partial charges for the residue.  The latter
> requires an MD simulation and a representative sample of quantum
> calculations to be run on geometries from the simulation.
>
> If what I just said makes no sense to you, then it will take a lot of
> work for you because you will have to learn all those things.  I don't
> know if any of the folks in our lab have time to spare to help you
> with this.  I don't know if we have time even to do any training right
> now, but might in the not too distant future.
>
> On Wed, Jun 26, 2019 at 1:44 AM R A Jeyaram 16PHD0482
> <[log in to unmask]> wrote:
> >
> > Dear Glycam Users,
> >
> >                  I am using Amber16 package and glycam force filed for
> MD simulation. My ligand file containing sialic acid and I substitute
> fluorine atom into O4 position of sialic acid. During the preparation of
> topology and parameter files via tleap module of Amber, I have the Fatal
> error as "Atom does not have file type" for fluorine atom. How can I
> parameterize fluorine atom.
> >                                         Thanks in Advance
> > with regards
> > R. A. Jeyaram
> > Research Scholar
> > School of Advanced Sciences
> > Vellore Institute of Technology
> > Tamil Nadu, India.
>
>
>
> --
> :-) Lachele
> Lachele Foley
> CCRC/UGA
> Athens, GA USA
>