Thanks, Paul.
Debbie
>>> Paul Mikkelsen <[log in to unmask]> 7/8/2007 10:54 PM >>>
I'm definitely not technically "up" on the topic, but FYI: there was a documentary on this condition in humans that was aired on the Discovery Health Channel. It was called: I am my own twin. Worth catching, if it re-airs.
This condition has major impacts to negative paternal tests... when if DNA from other tissues were taken, paternity would have been confirmed (i.e., in rare cases, as stated, a dead-beat-dad may incorrectly be determined not to be the father). Negative paternity tests should mean only that another test should be done using DNA from other tissues to confirm. Likewise, in rare cases, a known mother may be DNA tested and shown (not proved!) not to be the mother!
I've often wondered how prevalent this condition is in other species, and how much it may affect DNA studies... often taken as "gospel" by many. Although the documentary focused on humans, the concept was explained well.
Could/does this condition have implications (i.e., caution advised) elsewhere? ...in molluscs?
Could these issues, even if occurring at low frequency in a species, affect DNA tests which are used to help distinguish one species from another? ...or is this condition important only at an individual relationship level?
A very uninformed, but curious,
Paul
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Stemke Douglas wrote: I'm not that person, but can certainly answer part of the question. There are a few cases at least in humans, where 'different parts of the anatomy' could result in different human DNA. First many immune cells are the results of rearrangements and deleations so technically they are different (T-cells and B-cells anyway). Obviously sex cells, the results of meiosis, will have 'different' DNA as a result of recombination and reduction in the chromosome. The third one is rare, but in a VERY few number of human Chimeric individuals are known to exist, apparently one individual the result of a fusion between, what I would guess are two fertalized eggs. These individuals will have two completely different types of DNA from different tissues. Otherwise the remainder of the DNA should be the same.
Don't know if that helps.
Doug
Deborah Duval <[log in to unmask]> wrote:
Sorry to revisit this thread, but would whomever posted the comment about DNA from different parts of the anatomy of a given animal yielding different results, and therefore not necessarily solving all of the specie delimna, please show yourself so that I can pursue this a little further privately.
Thanks.
Debbie Duval
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